Compromised JMJD6 histone demethylase activity impacts on VHL gene repression in preeclampsia.
| Author | |
|---|---|
| Abstract | :
The von Hippel Lindau (VHL) protein is a key executor of the cellular hypoxic response that is compromised in preeclampsia, a serious disorder complicating 5-7% of pregnancies. To date, the mechanisms controlling VHL gene expression in the human placenta remain elusive. |
| Year of Publication | :
2018
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| Journal | :
The Journal of clinical endocrinology and metabolism
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| Date Published | :
2018
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| ISSN Number | :
0021-972X
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| DOI | :
10.1210/jc.2017-02197
|
| Short Title | :
J Clin Endocrinol Metab
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