This article studies theoretically the transportation of rheological viscoplastic fluids through physiological vessels by continuous muscle contraction and relaxation, that is, peristalsis. Both cases of planar and cylindrical physiological vessels are considered. A mathematical model is developed under long wavelength and low Reynolds number approximations. Expressions for axial velocity in core region, axial velocity in plug flow region, volume flow rate and pressure gradient in non-dimensional form are obtained. A comparative study of velocity profiles, pressure distribution, friction force and mechanical efficiency for different viscoplastic liquids is conducted. The influence of width of plug flow region, shear rate strain index and yield stress index on the pressure distribution, friction force and mechanical efficiency is elaborated. The study is relevant to gastric fluid mechanics and also non-Newtonian biomimetic pump hazardous waste systems exploiting peristaltic mechanisms.