Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder.
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| Abstract | :
Vitamin K deficiency in pregnant women causes intracranial hemorrhage (ICH) in fetuses. Fetal ICH frequently causes life-threatening and persistent neurological damage. However, indicators for preventing fetal ICH are not established. Two pregnant women developed long-term eating disorders caused by psychosis. They were administered intravenous fluid and vitamin supplementation, excluding vitamin K. The intracranial low-hypoechoic area on fetal ultrasound was suggestive of fetal ICH due to vitamin K deficiency. Their neonates showed severe developmental delay. Laboratory analysis revealed a normal prothrombin time, but elevated protein induced by vitamin K absence II. Pregnant women who have eating disorders more than 3 weeks could develop fetal ICH due to maternal subclinical vitamin K deficiency. Illness duration and protein induced by vitamin K absence II of pregnant woman may be indicators for vitamin K administration to prevent fetal intracranial hemorrhage. |
| Year of Publication | :
2019
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| Journal | :
The journal of obstetrics and gynaecology research
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| Volume | :
45
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| Issue | :
2
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| Number of Pages | :
461-465
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| ISSN Number | :
1341-8076
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| URL | :
https://doi.org/10.1111/jog.13825
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| DOI | :
10.1111/jog.13825
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| Short Title | :
J Obstet Gynaecol Res
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