Effects of ethanol, naltrexone, nicotine and varenicline in an ethanol and nicotine co-use model in Sprague-Dawley rats.
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| Abstract | :
As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both. We previously developed a model for ethanol (EtOH) and nicotine co-use in female selectively bred alcohol-preferring (P) rats. To model co-use in a genetically diverse population, we adapted the model to outbred Sprague-Dawley rats of both sexes and assessed the effect of drug pretreatments. |
| Year of Publication | :
2020
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| Journal | :
Drug and alcohol dependence
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| Volume | :
212
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| Number of Pages | :
107988
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| Date Published | :
2020
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| ISSN Number | :
0376-8716
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| URL | :
https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(20)30153-8
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| DOI | :
10.1016/j.drugalcdep.2020.107988
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| Short Title | :
Drug Alcohol Depend
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